Motif ID: FOX{F1,F2,J1}.p2

Z-value: 0.710


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXF1chr16_+_85101734-0.273.1e-01Click!
FOXJ1chr17_-_71648965-0.214.4e-01Click!
FOXF2chr6_+_1335067-0.019.6e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_190811479 0.883 NM_002922
RGS1
regulator of G-protein signaling 1
chr6_+_154373323 0.869 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr2_-_21084077 0.854 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_-_21084911 0.851 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_-_45410033 0.823 ZMYND8
zinc finger, MYND-type containing 8
chr14_+_31868229 0.576 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr5_-_58607673 0.562 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_42847716 0.560 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr5_+_147754467 0.535 FBXO38
F-box protein 38
chr9_+_128764324 0.534 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr7_+_134483305 0.521 NM_018295
TMEM140
transmembrane protein 140
chr4_+_70896236 0.495 NM_001009181
NM_003154
STATH

statherin

chr9_+_112470871 0.485 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr4_-_152368492 0.471 SH3D19
SH3 domain containing 19
chr2_-_121875610 0.462 CLASP1
cytoplasmic linker associated protein 1
chr1_-_246869181 0.457 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr5_-_142046175 0.428 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr9_-_14712669 0.425 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr12_+_77963563 0.424 NM_001135806
SYT1
synaptotagmin I
chr4_+_100714995 0.423 MTTP
microsomal triglyceride transfer protein
chr3_+_145174856 0.418 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr11_-_104274606 0.415 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr16_+_27248806 0.414 IL4R
interleukin 4 receptor
chr9_-_3213007 0.411


chr4_+_91375204 0.406 NM_207491
FAM190A
family with sequence similarity 190, member A
chr6_-_128281434 0.399 NM_001164687
THEMIS
thymocyte selection associated
chr6_+_64403668 0.390 PHF3
PHD finger protein 3
chr8_+_50987149 0.387 NM_018967
SNTG1
syntrophin, gamma 1
chr13_+_49658016 0.381


chr1_+_74473672 0.381 NM_015978
TNNI3K
TNNI3 interacting kinase
chr11_-_107969554 0.377 NM_015065
EXPH5
exophilin 5
chr4_-_123761615 0.376 NM_021803
IL21
interleukin 21
chr12_-_89976261 0.368 NM_007035
KERA
keratocan
chr5_+_81636921 0.360 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr1_-_103269356 0.356 COL11A1
collagen, type XI, alpha 1
chr17_-_36276987 0.350 NM_000223
KRT12
keratin 12
chr4_+_146623405 0.345 NM_001003688
SMAD1
SMAD family member 1
chr6_-_50025115 0.345 NM_001166478
DEFB133
defensin, beta 133
chr12_-_44919818 0.343 SLC38A1
solute carrier family 38, member 1
chr15_-_68781662 0.340 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr13_-_98708549 0.340 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr20_+_31905088 0.340 CHMP4B
chromatin modifying protein 4B
chr22_-_31732648 0.339 NM_003490
NM_133633
SYN3

synapsin III

chr4_+_72321113 0.338 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr2_+_219354692 0.337 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr8_-_9451439 0.334


chr3_+_110024234 0.331 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr2_-_36929520 0.331 STRN
striatin, calmodulin binding protein
chr18_-_23019176 0.329 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr18_+_30327341 0.320 DTNA
dystrobrevin, alpha
chr1_+_221168388 0.315 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr7_+_93373755 0.314 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_+_99934227 0.314 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr3_+_142143329 0.314 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr2_-_215951161 0.312 FN1
fibronectin 1
chr7_+_116151411 0.308 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr17_-_5078773 0.302 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr10_+_4995597 0.300 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_147775652 0.299 FBXO38
F-box protein 38
chr2_+_204440753 0.295 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr5_+_32824701 0.294 NM_024563
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_-_150564302 0.294 NM_002016
FLG
filaggrin
chr18_+_53170718 0.285 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_191009265 0.280 MFSD6
major facilitator superfamily domain containing 6
chr6_+_136214495 0.280 NM_018945
PDE7B
phosphodiesterase 7B
chr10_+_4995453 0.273 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr1_+_144149794 0.273 NM_006472
TXNIP
thioredoxin interacting protein
chr17_+_69939130 0.271 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_+_52027020 0.268 RBL2
retinoblastoma-like 2 (p130)
chr4_+_69716298 0.267 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr3_-_127138571 0.267 NM_001015050
NM_001195223
ALG1L

asparagine-linked glycosylation 1-like

chr11_-_102331643 0.264 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr7_+_142053693 0.258 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr7_-_122422989 0.256 NM_016945
TAS2R16
taste receptor, type 2, member 16
chr1_-_184916044 0.255 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_137224266 0.251 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_215955206 0.250 FN1
fibronectin 1
chr10_+_4995685 0.250 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_-_90702490 0.247 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_-_27074407 0.246 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr17_-_3142625 0.246 NM_002550
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr4_+_35962038 0.245 NM_001170700
DTHD1
death domain containing 1
chr13_+_20081940 0.244


chr4_-_87247829 0.242 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr11_-_5178505 0.241 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr7_+_142590633 0.241 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr1_-_155834357 0.240 NM_031282
FCRL4
Fc receptor-like 4
chr3_-_58497913 0.238 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr14_-_105549177 0.238 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr7_-_81237162 0.235 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr10_+_111975618 0.234 NM_005962
MXI1
MAX interactor 1
chr22_+_19458378 0.234 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_-_105785639 0.232


chr14_+_21203136 0.230 NM_001001912
OR4E2
olfactory receptor, family 4, subfamily E, member 2
chr6_+_97117144 0.229 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr20_+_9406460 0.228 PLCB4
phospholipase C, beta 4
chr5_-_20024050 0.225 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr18_+_30327243 0.223 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr12_-_11439752 0.222 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr14_+_20226762 0.221 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_+_95621492 0.219 NM_138800
TRIM43
tripartite motif containing 43
chr12_-_44644216 0.218


chr2_-_192419896 0.214 SDPR
serum deprivation response
chr6_+_4781330 0.214 NM_001143970
CDYL
chromodomain protein, Y-like
chrX_+_57635165 0.213 ZXDB
zinc finger, X-linked, duplicated B
chr1_+_47305633 0.213 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr2_+_178893216 0.211 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr5_-_36337756 0.210 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr8_-_133841988 0.209 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr14_-_105900687 0.209 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2
chr2_-_95514205 0.208 NM_001164464
TRIM43
TRIM43B
tripartite motif containing 43
tripartite motif containing 43B
chr11_+_57738792 0.208 NM_001004458
OR1S1
olfactory receptor, family 1, subfamily S, member 1
chr6_-_29081015 0.207 NM_001010877
ZNF311
zinc finger protein 311
chr6_+_21774624 0.207 FLJ22536
hypothetical locus LOC401237
chr20_-_43609409 0.206 NM_001198986
NM_020398
SPINLW1-WFDC6
SPINLW1
SPINLW1-WFDC6 readthrough
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr18_+_29573152 0.205 ASXL3
additional sex combs like 3 (Drosophila)
chr5_-_13997588 0.204 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr4_-_21559471 0.204 NM_147182
KCNIP4
Kv channel interacting protein 4
chr4_-_107508040 0.204 NM_001195138
LOC100507096
GTPase IMAP family member-like
chr19_+_18357966 0.203 NM_004864
GDF15
growth differentiation factor 15
chr2_-_218739891 0.203 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr9_-_41944687 0.202 MGC21881
hypothetical locus MGC21881
chr17_-_36877002 0.202 NM_002278
KRT32
keratin 32
chr2_-_150152482 0.201 MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr20_+_35266581 0.199 RPN2
ribophorin II
chr2_-_225078931 0.199 CUL3
cullin 3
chr4_+_172971149 0.195 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr6_-_32892705 0.195 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr18_+_53863865 0.195 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_118976134 0.194 NM_002667
PLN
phospholamban
chr8_-_6901661 0.194 NM_021010
DEFA5
defensin, alpha 5, Paneth cell-specific
chr10_-_31328426 0.193 NM_001143769
ZNF438
zinc finger protein 438
chr12_-_10464308 0.191 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr2_-_165133239 0.190 GRB14
growth factor receptor-bound protein 14
chr6_+_108988797 0.188 FOXO3
forkhead box O3
chr11_+_60016826 0.187 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr7_+_50318801 0.186 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr6_+_84619703 0.186 NM_001009994
RIPPLY2
ripply2 homolog (zebrafish)
chrX_-_33267646 0.186 NM_000109
DMD
dystrophin
chrX_+_100220491 0.185 NM_021637
TMEM35
transmembrane protein 35
chr2_+_86800898 0.185 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_198088997 0.184 NM_001100819
NM_015387
MOBKL3

MOB1, Mps One Binder kinase activator-like 3 (yeast)

chr5_+_65258316 0.181 ERBB2IP
erbb2 interacting protein
chr17_-_36403910 0.181 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr1_-_150599105 0.181 NM_001014342
FLG2
filaggrin family member 2
chr1_+_183970093 0.180 NM_031935
HMCN1
hemicentin 1
chr20_+_16676997 0.180 NM_020157
OTOR
otoraplin
chr2_-_215957927 0.180 FN1
fibronectin 1
chr6_-_127822227 0.179 NM_014702
KIAA0408
KIAA0408
chr20_-_33783409 0.179 RBM39
RNA binding motif protein 39
chr2_-_40510923 0.179 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr12_-_14929991 0.178 NM_000900
NM_001190839
MGP

matrix Gla protein

chr3_-_192531018 0.177 NM_198152
UTS2D
urotensin 2 domain containing
chr2_-_55413253 0.175 CCDC88A
coiled-coil domain containing 88A
chr7_+_28418668 0.174 NM_182898
CREB5
cAMP responsive element binding protein 5
chr15_-_48198697 0.174 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr11_-_55661769 0.173 NM_001004064
OR8J3
olfactory receptor, family 8, subfamily J, member 3
chr2_-_150152361 0.173 MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_+_552913 0.170


chr2_+_196229715 0.170 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr6_-_2696152 0.170 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr1_+_81544432 0.169 LPHN2
latrophilin 2
chr1_+_246682699 0.169 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr2_+_86801081 0.168 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr10_+_97749837 0.167 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr2_+_100453375 0.166 NM_001011717
NMS
neuromedin S
chr11_+_4564596 0.166 NM_001005170
OR52I2
olfactory receptor, family 52, subfamily I, member 2
chr4_+_88973144 0.165 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr2_-_150152531 0.163 NM_015702
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr2_-_192420168 0.163 NM_004657
SDPR
serum deprivation response
chr20_-_43732291 0.160 NM_147197
WFDC11
WAP four-disulfide core domain 11
chr6_+_64289585 0.159 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_+_58625086 0.159 TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_-_52217185 0.157 NM_052872
IL17F
interleukin 17F
chr18_+_58533597 0.156 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr20_+_56912146 0.156 GNAS
GNAS complex locus
chr6_-_29120930 0.156 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr2_+_86800940 0.155 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr4_-_120445047 0.155 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr20_+_21054623 0.152 NM_001163022
NM_001163023
NM_018474
PLK1S1


polo-like kinase 1 substrate 1


chr7_-_83108682 0.151 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr5_+_38439399 0.150 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr1_-_148936123 0.150 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr11_-_9182356 0.149 DENND5A
DENN/MADD domain containing 5A
chr2_+_214984705 0.149 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chrX_-_15243647 0.148 NM_080873
ASB11
ankyrin repeat and SOCS box containing 11
chr2_-_39310176 0.148 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chrX_+_78087484 0.147 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chrX_+_109548940 0.147 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr10_+_60606352 0.147 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr1_+_169747788 0.147 PRRC2C
proline-rich coiled-coil 2C
chr6_+_108988761 0.146 NM_001455
FOXO3
forkhead box O3
chr4_-_20594645 0.145 KCNIP4
Kv channel interacting protein 4
chr22_+_35639564 0.145 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr4_-_186537145 0.142 NM_018409
LRP2BP
LRP2 binding protein
chr9_+_90193807 0.142 SPIN1
spindlin 1
chr11_-_58947001 0.141 NM_001001954
OR5A2
olfactory receptor, family 5, subfamily A, member 2
chr8_+_79591074 0.140 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr22_-_15682555 0.139 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr3_-_57301749 0.139 NM_001142733
ASB14
ankyrin repeat and SOCS box containing 14

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.27 7.10e-06 GO:0007608 sensory perception of smell
2.17 1.29e-05 GO:0007606 sensory perception of chemical stimulus
1.68 3.86e-03 GO:0007600 sensory perception

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 1.86e-06 GO:0005886 plasma membrane
1.32 1.94e-06 GO:0071944 cell periphery
1.14 8.77e-03 GO:0016020 membrane
2.34 1.58e-02 GO:0005882 intermediate filament
1.18 2.40e-02 GO:0016021 integral to membrane
1.17 3.89e-02 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 1.49e-06 GO:0004930 G-protein coupled receptor activity
2.30 2.02e-06 GO:0004984 olfactory receptor activity
1.61 2.29e-05 GO:0004888 transmembrane receptor activity
1.43 2.19e-03 GO:0004872 receptor activity
1.32 3.95e-02 GO:0004871 signal transducer activity
1.32 3.95e-02 GO:0060089 molecular transducer activity